Wednesday, October 26, 2016

CalCough Infant Syrup





1. Name Of The Medicinal Product



Benylin Children's Apple Flavour Cough Syrup or CalCough Infant Syrup


2. Qualitative And Quantitative Composition









Active ingredient


% v/v



ml/5ml


Glycerol



For excipients see 6.1



15.0

0.75


3. Pharmaceutical Form



Syrup



A clear colourless syrup with an apple flavour.



4. Clinical Particulars



4.1 Therapeutic Indications



For the relief of dry tickly coughs.



4.2 Posology And Method Of Administration



Oral use.



Children 3 months - 1 year: one 5ml spoonful three to four times a day.



Children 1 to 5 years: two 5ml spoonfuls three to four times a day.



Children under 3 months: not recommended.



4.3 Contraindications



Hypersensitivity to any of the ingredients.



Not recommended for children under 3 months.



Patients with rare hereditary problems of fructose intolerance should not take this medicine.



4.4 Special Warnings And Precautions For Use



If symptoms persist for more than 3 days consult your doctor.



Keep all medicines out of the reach of children.



4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction



No clinically significant drug interactions.



4.6 Pregnancy And Lactation



Not applicable.



4.7 Effects On Ability To Drive And Use Machines



No or negligible influence.



4.8 Undesirable Effects



Maltitol may have a mild laxative effect.



4.9 Overdose



Overdosage with this product may possibly cause diarrhoea. Treatment should be symptomatic.



5. Pharmacological Properties



5.1 Pharmacodynamic Properties



The ATC code is R05FB01.



Glycerol has demulcent properties and may possibly block sensory cough receptors in the respiratory tract.



5.2 Pharmacokinetic Properties



Glycerol is readily absorbed from the gastrointestinal tract and undergoes extensive metabolism principally in the liver. It may be used in the synthesis of lipids, and is metabolised to glucose or glycogen or oxidized to carbon dioxide and water. It may also be excreted in the urine unchanged.



5.3 Preclinical Safety Data



Not applicable



6. Pharmaceutical Particulars



6.1 List Of Excipients



Maltitol liquid (E965)



Hydroxyethylcellulose



Sodium benzoate



Citric acid monohydrate



Sodium citrate



Apple flavouring 5112OIE



Purified water



6.2 Incompatibilities



None stated



6.3 Shelf Life



3 years



6.4 Special Precautions For Storage



Keep the bottle tightly closed.



Do not store above 25°C.



6.5 Nature And Contents Of Container



1) Bottle amber PET with polypropylene child resistant closure fitted with expanded polythene liner.



A spoon with a 5 ml and 2.5 ml measure is supplied with this pack.



Pack size: 100 ml and 150 ml.



Contained in a box board carton.



2) Bottle amber glass with polypropylene child resistant closure fitted with an expanded polyethylene liner.



A spoon with a 5 ml and 2.5 ml measure is supplied with this pack.



Pack size 100, 125ml or 150ml.



Contained in a box board carton.



Not all pack sizes may be marketed.



6.6 Special Precautions For Disposal And Other Handling



Not applicable



7. Marketing Authorisation Holder



McNeil Products Limited



Foundation Park



Roxborough Way



Maidenhead



Berkshire SL6 3UG



United Kingdom



8. Marketing Authorisation Number(S)



PL 15513/0168



9. Date Of First Authorisation/Renewal Of The Authorisation



19 March 2009



10. Date Of Revision Of The Text



03 October 2009




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